Download Animal Models for the Study of Human Disease by P. Michael Conn PDF

By P. Michael Conn

Animal versions for the research of Human Disease identifies vital animal versions and assesses the benefits and downsides of every version for the examine of human disorder. The first part addresses easy methods to find assets, animal choices, animal ethics and similar concerns, a lot wanted details for researchers around the organic sciences and biomedicine.The subsequent sections of the paintings bargains types for disease-oriented subject matters, together with cardiac and pulmonary illnesses, getting older, infectious illnesses, weight problems, diabetes, neurological ailments, joint illnesses, visible problems, melanoma, high blood pressure, genetic illnesses, and illnesses of abuse.

  • Organized by means of illness orientation for ease of searchability
  • Provides details on finding assets, animal possible choices and animal ethics
  • Covers a vast variety of animal versions utilized in learn for human disease

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Extra info for Animal Models for the Study of Human Disease

Sample text

But pigs are extremely sophisticated mentally and socially, perhaps no less so than dogs. What seems to distinguish pigs from dogs is not that dogs are “higher” animals, but that in the US and most countries dogs are beloved pets and pigs are food. Rowan and I have suggested90 a number of criteria for distinguishing among species in ways that support demanding a stronger showing of the value of research in using certain species. These criteria include whether animals exhibit self-awareness, their mental complexity, the complexity of their natural social behavior, and whether and how they interact with human beings.

22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 1. ETHICS IN BIOMEDICAL ANIMAL RESEARCH Reed JC, White EL, Aube´ J, Lindsley C, Li M, Sklar L, et al. The NIH’s role in accelerating translational sciences. Nat Biotechnol 2010;30(1):16–9. Zerhouni EA. Translational research: Moving discovery to practice. Clin Pharmacol Ther 2007;81(1):126–8. Zucker DR. What is needed to promote translational research and how do we get it? J Investig Med 2009;57(2):468–70. Midgley M. Why knowledge matters. In: Sperlinger D, editor.

Kraus AL, Renquist D, editors. Bioethics and the use of laboratory animals: Ethics in theory and practice. Chester, NH: American College of Laboratory Animal Medicine; 2001. 103. Paul EF, Paul J, editors. Why animal experimentation matters: The use of animals in medical research. New Brunswick, NJ: Transaction; 2001. 104. Morrison AR. An odyssey with animals: A veterinarian’s reflection on the animal rights and welfare debate. New York: Oxford University Press; 2009. C H A P T E R 2 Access to Resources A Model Organism Database for Humans Judith Axler Turner TCG, Washington, DC, USA O U T L I N E The Problem 37 The LAMHDI Solution LAMHDI Database Search Some Sources are Curatorial Some Sources Provide the Model Information Performing the Search 38 39 39 39 41 The Advantages and Limitations of LAMHDI The Ideal Solution 45 Acknowledgments 46 References 47 THE PROBLEM and not the model.

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